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If you have a severe allergic reaction, anaphylaxis, or cardiovascular event during treatment, the nurse's options are limited to calling 911 and providing basic first aid while waiting for paramedics

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Activation of PKC isoenzymes by ROS may entail phosphorylation of certain tyrosine residues that lie adjacent to the regulatory domain by non-receptor-type kinases [214], possibly by c-Abl [190], but it may also occur via oxidation of Cys residues in its regulatory or catalytic domains [215]